MCS

Music

• Motion City Soundtrack, a pop punk / rock band from Minneapolis, Minnesota

Science and technology

• Mars Climate Sounder instrument, on Mars Reconnaissance Orbiter spacecraft
• MAssive Cluster Survey abbreviated as either MACS or MCS
• Matrix cable system, submarine communications cable connecting Indonesia and Singapore
• Megawatt Charging System, electric vehicle charging connector
• Mercalli-Cancani-Sieberg scale, a scale of earthquake intensity, successor to the Mercalli intensity scale
• Mesoscale convective system, a complex of thunderstorms
• Modulation and coding scheme, in the telecommunications industry

Biology and medicine

• Membrane contact site, within cells
• Minimally conscious state, a disorder of consciousness
• Multiple chemical sensitivity, an unrecognized and controversial medical diagnosis characterized by chronic symptoms attributed to exposure to low levels of commonly used chemicals
• Multiple cloning site, the region of restriction enzyme sites in a plasmid

Computing

• Master of Computer Science
• Multiple Console Support, in OS/360 and successors
• Multi categories security, in Security-Enhanced Linux
• Multinational Character Set, used in VT220 terminals
• Music Construction Set, a music composition notation program
• MCS algorithm (Multilevel Coordinate Search), a derivative-free optimization algorithm
• Micro Computer Set (disambiguation), various Intel microprocessor architectures

Organizations

• Marcus Corporation (NYSE symbol)
• Marine Conservation Society, UK
• Methodist Church in Singapore
• MCS (fashion brand) (formerly Marlboro Classics), an Italian clothing brand
• Muslim Council of Scotland

Schools

Canada

• Master's College and Seminary, Peterborough, Ontario

Hong Kong

• Maryknoll Convent School, Kowloon Tong

Ireland

• Malahide Community School, Dublin

Philippines

• Malate Catholic School, Manila
• Mater Carmeli School, Quezon City, Metro Manila

Pakistan

• Military College of Signals, Rawalpindi, Punjab
• Murree Christian School, Jhika Gali, Punjab

United Kingdom

• Magdalen College School, Oxford, England
• Magdalen College School, Brackley, England
• Michaela Community School, London, England

United States

• Manhattan Country School, New York
• McMinn County Schools, Tennessee
• Mellon College of Science, Carnegie Mellon University, Pittsburgh, Pennsylvania
• Montrose Christian School, Rockville, Maryland
• Murfreesboro City Schools, Murfreesboro, Tennessee

Other uses

• Master of Christian Studies (MCS)
• A US Navy hull classification symbol: Mine countermeasures support ship (MCS)
• Management control system
• Michigan Central Station, a former rail station depot in Detroit, Michigan, US
• Millennium Cohort Study, UK